CVE-2026-21997
Quick assessment
Affected
Oracle Corporation Oracle Life Sciences Empirica Signal
Exploitation
No confirmed in-the-wild exploitation; assess based on exposure
Recommended action
Check the vendor advisory and references for a fixed version. If immediate upgrade is impossible, restrict exposure and increase monitoring.
Oracle Life Sciences Empirica Signal是美国甲骨文（Oracle）公司的一款药物安全信号检测平台。 Oracle Life Sciences Empirica Signal 9.2.1版本至9.2.3版本存在安全漏洞，该漏洞源于Common Core组件问题，可能导致权限低的攻击者通过HTTP网络访问，授权创建、删除或修改关键数据或所有数据以及读取部分数据。
Possible ATT&CK Techniques 2 AI
T1059 · Command and Scripting Interpreter T1190 · Exploit Public-Facing Application
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I. Basic Information for CVE-2026-21997
Vulnerability Information
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Vulnerability Title
N/A
Source: CVE Program / CVE List V5
Vulnerability Description
Vulnerability in the Oracle Life Sciences Empirica Signal product of Oracle Life Science Applications (component: Common Core). Supported versions that are affected are 9.2.1-9.2.3. Easily exploitable vulnerability allows low privileged attacker with network access via HTTP to compromise Oracle Life Sciences Empirica Signal. While the vulnerability is in Oracle Life Sciences Empirica Signal, attacks may significantly impact additional products (scope change). Successful attacks of this vulnerability can result in unauthorized creation, deletion or modification access to critical data or all Oracle Life Sciences Empirica Signal accessible data as well as unauthorized read access to a subset of Oracle Life Sciences Empirica Signal accessible data. CVSS 3.1 Base Score 8.5 (Confidentiality and Integrity impacts). CVSS Vector: (CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N).
Source: CVE Program / CVE List V5
CVSS Information
CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N
Source: CVE Program / CVE List V5
Vulnerability Type
N/A
Source: CVE Program / CVE List V5
Vulnerability Title
Oracle Life Sciences Empirica Signal 安全漏洞
Source: CNNVD (China National Vulnerability Database)
Vulnerability Description
Oracle Life Sciences Empirica Signal是美国甲骨文（Oracle）公司的一款药物安全信号检测平台。 Oracle Life Sciences Empirica Signal 9.2.1版本至9.2.3版本存在安全漏洞，该漏洞源于Common Core组件问题，可能导致权限低的攻击者通过HTTP网络访问，授权创建、删除或修改关键数据或所有数据以及读取部分数据。
Source: CNNVD (China National Vulnerability Database)
CVSS Information
N/A
Source: CNNVD (China National Vulnerability Database)
Vulnerability Type
N/A
Source: CNNVD (China National Vulnerability Database)
Affected Products
| Vendor | Product | Affected Versions | CPE | Subscribe |
|---|---|---|---|---|
| Oracle Corporation | Oracle Life Sciences Empirica Signal | 9.2.1 ~ 9.2.3 | - |
|
II. Public POCs for CVE-2026-21997
| # | POC Description | Source Link | Shenlong Link |
|---|
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Vendor Advisories for CVE-2026-21997 (1)
-
https://www.oracle.com/security-alerts/cpuapr2026.html vendor-advisory
Same Patch Batch · Oracle Corporation · 2026-04-21 · 102 CVEs total
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| CVE-2026-35251 | 7.5 HIGH | Oracle VM VirtualBox 安全漏洞 |
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| CVE-2026-35245 | 7.5 HIGH | Oracle VM VirtualBox 安全漏洞 |
| CVE-2026-35242 | 7.5 HIGH | Oracle VM VirtualBox 安全漏洞 |
| CVE-2026-35230 | 7.5 HIGH | Oracle VM VirtualBox 安全漏洞 |
Showing top 20 of 102 CVEs. View all on vendor page → →
IV. Related Vulnerabilities
V. Comments for CVE-2026-21997
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