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I. Basic Information for CVE-2026-31969
Vulnerability Information

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Vulnerability Title
HTSlib CRAM decoder has a heap buffer overflow
Source: NVD (National Vulnerability Database)
Vulnerability Description
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Source: NVD (National Vulnerability Database)
CVSS Information
N/A
Source: NVD (National Vulnerability Database)
Vulnerability Type
堆缓冲区溢出
Source: NVD (National Vulnerability Database)
Vulnerability Title
HTSlib 缓冲区错误漏洞
Source: CNNVD (China National Vulnerability Database)
Vulnerability Description
HTSlib是samtools开源的一个C语言的库文件。 HTSlib 1.23.1之前版本、1.22.2之前版本和1.21.1之前版本存在缓冲区错误漏洞,该漏洞源于cram_byte_array_stop_decode_char函数存在差一错误,可能导致堆缓冲区溢出。
Source: CNNVD (China National Vulnerability Database)
CVSS Information
N/A
Source: CNNVD (China National Vulnerability Database)
Vulnerability Type
N/A
Source: CNNVD (China National Vulnerability Database)
Affected Products
VendorProductAffected VersionsCPESubscribe
samtoolshtslib < 1.21.1 -
II. Public POCs for CVE-2026-31969
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III. Intelligence Information for CVE-2026-31969
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IV. Related Vulnerabilities
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