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CVE-2026-100845— MONAI before 1.6.0 Remote Code Execution via NumpyReader

Quick assessment

Affected
Project-MONAI MONAI
Exploitation
No confirmed in-the-wild exploitation; assess based on exposure
Recommended action
Check the vendor advisory and references for a fixed version. If immediate upgrade is impossible, restrict exposure and increase monitoring.

在 MONAI 1.6.0 版本之前,NumpyReader 类中存在不安全的反序列化漏洞。该漏洞在加载 .npy 和 .npz 文件时,无条件地使用 numpy.load 并设置 allow_pickle=True。攻击者可以构造带有恶意 pickle 负载的 .npy 文件,当这些文件通过 MONAI 的标准数据管道加载时,将执行任意代码。

CVSS 7.8 · High EPSS 0.14% · P3
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I. Basic Information for CVE-2026-100845

Vulnerability Information

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Vulnerability Title
MONAI before 1.6.0 Remote Code Execution via NumpyReader
Source: CVE Program / CVE List V5
Vulnerability Description
MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.
Source: CVE Program / CVE List V5
CVSS Information
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Source: CVE Program / CVE List V5
Vulnerability Type
可信数据的反序列化
Source: CVE Program / CVE List V5

Affected Products

Vendor Product Affected Versions CPE Subscribe
Project-MONAI MONAI 0 ~ 1.6.0 -

II. Public POCs for CVE-2026-100845

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III. Intelligence Information for CVE-2026-100845

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Vendor Advisories for CVE-2026-100845 (1)

Other References for CVE-2026-100845 (1)

Same Patch Batch · Project-MONAI · 2026-09-27 · 7 CVEs total

CVE-2026-100844 8.4 HIGH MONAI before 1.6.0 OS Command Injection via dataset_name_or_id
CVE-2026-100841 7.8 HIGH MONAI through 1.6.0 PersistentDataset Remote Code Execution via Pickle Cache
CVE-2026-100843 7.8 HIGH MONAI before 1.6.0 Remote Code Execution via algo_from_pickle
CVE-2026-100840 7.8 HIGH MONAI through 1.6.0 Remote Code Execution via bundle configuration
CVE-2026-100846 7.6 HIGH MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization
CVE-2026-100842 7.0 HIGH MONAI through 1.6.0 _get_fake_spatial_shape eval() Sandbox Bypass via Attribute Chains

IV. Related Vulnerabilities

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